Champions Manchester City kickstart their title defence away to Arsenal in an explosive start to the new 2018/19 season.
New Gunners boss Unai Emery is presented with a tough start at home to last season’s runaway winners, with Pep Guardiola’s men backed by the bookies as the favourites to win the Premier League again.
Manchester United will entertain 2015/16 champions Leicester at Old Trafford on the opening day of the new campaign on August 11.
Last season’s beaten Champions League finalists Liverpool welcome West Ham and their new manager Manuel Pellegrini to Anfield first up.
Marco Silva will get his Everton reign up and running with a visit to newly-promoted Wolves at Molineux.
Fellow new boys Cardiff travel to Bournemouth, while play-off winners Fulham entertain London rivals Crystal Palace at Craven Cottage.
Huddersfield clinched survival last May by holding Chelsea to a draw at Stamford Bridge. And David Wagner’s men will start their season at home to the Blues.
Tottenham, meanwhile, travel to Newcastle again on the opening day – just as they did last year, where they won 2-0.
Spurs have their new stadium to look forward to. And it Liverpool who will be the first visitors to the new White Hart Lane on September 15 with Mauricio Pochettino’s side returning to Wembley for their August 18 home game against Fulham.
Elsewhere, Watford kickstart their term at home to Europa League fodder Burnley.
The first Manchester Derby on the new season is on November 10 with champions City hosting United at the Etihad Stadium. Arsenal will take on Tottenham in the first North London derby of the new season on December 1 with the Merseyside derby between Liverpool and Everton on the same day – along with Chelsea versus Fulham.
Boxing Day sees West Ham on the road against Southampton with Liverpool taking on Newcastle and Manchester United hosting Huddersfield.
The final day of the season sees Manchester City travel to Brighton, United at home to Cardiff, Liverpool hosting Wolves, Arsenal up against Brighton and Chelsea away at Leicester.
Bournemouth v Cardiff City
Arsenal v Manchester City
Fulham v Crystal Palace
Huddersfield Town v Chelsea
Liverpool v West Ham United
Manchester United v Leicester City
Newcastle v Tottenham Hotspur
Southampton v Burnley
Watford v Brighton
Wolves v Everton